Take home points on electrophiles: 1) They want electrons, meaning they are electron deficient, in order to form a new bond. 2) They are attacked by nucleophiles. 3) They are positively charged (or have a partial positive), polar and/or polarizable. 4) They become even better electrophiles in the presence of Lewis acids.Properties In general, in a group across the periodic table, the more basic the ion (the higher the pK a of the conjugate acid) the more reactive it is as a nucleophile. Within a series …𝐃𝐨𝐰𝐧𝐥𝐨𝐚𝐝 𝐀𝐓𝐏 𝐒𝐓𝐀𝗥 𝐀𝐩𝐩 𝐟𝐨𝐫 Unlimited free practice for IIT 𝐉𝐄𝐄 📱 𝐀𝐓𝐏 𝐒𝐓𝐀𝗥 𝗔𝗽𝗽 ...Nov 30, 2012 · 2. “Strong” vs. “Weak” Nucleophiles / Bases. Now that we have had some practice in identifying the likely nucleophile, I am going to suggest a somewhat rough but very helpful classification that will help in distinguishing S N 1/E1 reactions from S N 2/E2 reactions. Jun 5, 2012 · Table of Contents A Nucleophile Is A Reactant That Provides A Pair Of Electrons To Form A New Covalent Bond An Electrophile Is A Reactant That Accepts A Pair Of Electrons To Form A New Covalent Bond Nucleophilicity” And “Electrophilicity” Refer To The Extent To Which A Species Can Donate Or Accept A Pair Of Electrons Feb 13, 2019 · 1. Recognizing organic compounds as nucleophiles or electrophiles is an important first step in recognizing and learning patterns of chemical reactivity. Classify the following compounds as nucleophiles or electrophiles. a) methoxide (CH 3 O -) b) formaldehye (CH 2 O) c) bromocyclopentane. d) water. e) sodium cyanide. Chad introduces nucleophiles and electrophiles in the context of nucleophilic attack, one of the common mechanistic steps of organic reactions. He explains ...Oct 20, 2023 · Key Differences. Electrophiles and nucleophiles are foundational concepts in organic chemistry, driving many reactions. An electrophile is typically a molecule or ion that is electron-poor and has an affinity for electrons. It "loves" electrons and tends to attract them. Conversely, a nucleophile is an electron-rich molecule or ion, which has a ... Aug 21, 2023 ... Electrophilic addition reactions often involve unsaturated compounds like alkenes and alkynes, while nucleophilic addition reactions typically ...A majority of the organic chemistry reactions we’ll discuss essentially deal with the interactions between nucleophiles and electrophiles: an electrophile accepts an electron pair donated by a nucleophile which results in the formation of a bond . In organic chemistry, most electrophiles involve an electrophilic carbon. 2. NUCLEOPHILE The term nucleophile is composed of two words nucleo and –phile.the -phile suffix used in lot of words mean lover of whatever comes in front. So the nucleophile is the lover of nucleus . Loving nuclei mean loving positive charges.So the lover of positive charges must be negatively charged. A nucleophile is an ion or …This lecture is about electrophile and nucleophile in chemistry. I will teach you the basic concept of electrophiles and nucleophiles with easy examples. Af...Abstract. Electrophiles are electron deficient species and can accept an electron pair from electron rich species. Examples include carbocations and carbonyl compounds. A nucleophile is electron ...An electrophile is an electron-poor molecule that can form covalent bonds by accepting electrons from a nucleophile, an electron-rich molecule. In organic reactions, many molecules can act as an electrophile, but there are certain ways a molecule can become one. Learn more about electrophiles below!6.5. Lewis acids & bases, electrophiles & nucleophiles. Acids and bases are an important part of organic chemistry. One of the most applicable theories is the Lewis acid/base motif that extends beyond the Br ø nsted-Lowry definition described in the previous section. In order for the nucleophile to attack the electrophile, it must break free, at least in part, from its solvent cage. The lone pair electrons on the larger, less basic iodide ion interact less tightly with the protons on the protic solvent molecules - thus the iodide nucleophile is better able to break free from its solvent cage compared the ...History Nucleophile vs Electrophile Explained Applications Examples for Nucleophile vs Electrophile FAQs History A British chemist named Christopher Kelk Ingold from …the alkene is a nucleophile and bromine is acting as an electrophile and the mechanism step is an example of “Make a bond between a nucleophile and electrophile”. Note that a lone pair on bromine simultaneously makes a second new bond with the alkene to give the three-membered ring reaction intermediate. Also notice that the Br An electrophile is an electron-deficient atom,, ion or molecule while the nucleophile is an electron-rich atom, molecule or ion. An electrophile can be positively or neutrally charged while the nucleophile can be negatively or neutrally charged. An electrophile is called the Lewis acid and the nucleophile is called the Lewis base.An electrophile is a molecule or chemical functional group with an electron-deficient atom that accepts electrons from a nucleophile to form a covalent bond.1. The difference between nucleophiles and bases includes the role they play in a chemical reaction. 2. Nucleophiles react to speed or energy while bases react to various temperatures. 3. Nucleophiles are involved in electrophilicity while bases are involved in bacisity reactions. 4.Jul 3, 2017 · The main difference between electrophile and nucleophile is that electrophiles are atoms or molecules that can accept electron pairs whereas nucleophiles are atoms or molecules that can donate electron pairs. References: 1. “Nucleophile.” Chemistry LibreTexts. Libretexts, 21 July 2016. Web. 27 June 2017. 2. “Nucleophiles and Electrophiles ... What is a Nucleophile. A nucleophile is a reagent consisting of an atom, ion, or molecule that donates electron pair to form a bond. It is an electron-rich species that can be negatively charged or neutral with available …Electrophiles and nucleophiles are chemical substances that accept/donate electrons to form a chemical bond.To summarize, when we’re talking about basicity and nucleophilicity, we’re talking about these two types of events. Basicity: nucleophile attacks hydrogen. Nucleophilicity: nucleophile attacks any atom other than hydrogen. Because we’re talking about organic chemistry here, for our purposes, this is going to mean “carbon” most of …Organic reactions are kind of like carefully choreographed fight scenes, and nucleophilic attack is a key move. This episode of Crash Course Organic Chemistr...Jul 20, 2020 ... The nucleophiles and electrophiles are the two fundamental species in organic chemistry. Nucleophiles ... 17.2 Aromatic vs Antiaromatic vs ...According to what my professor taught me, both $\ce{SO3}$ and $\ce{SO3H+}$ may be the electrophile involved - and mechanisms with both species can be successfully written. I'm looking for some source(s) that confirms the existence of both electrophiles in sulfonation reaction of benzene.Technically, under the definitions of nucleophile and electrophile all Brønsted acid-base reactions are also nucleophile-electrophile reactions (Figure 7.6).An electrophile is a chemical species that accepts an electron pair and forms bonds with nucleophiles. Electrophiles are Lewis acids because they accept electrons.Most electrophiles are positively charged, have a partial positive charge on an atom, or have an atom without an octet of electrons.. Addition and substitution reactions are the most …Feb 13, 2019 ... b) electrophile (Carbonyl carbon has partial positive charge.) c) electrophile (Alkyl halides are always electrophiles - one reason they are an ...Learn how to identify nucleophiles and electrophiles in organic molecules based on electronegativity and charge distribution. Watch a video and see examples, definitions, …Once again, steric hindrance - this time caused by bulky groups attached to the electrophile rather than to the nucleophile - hinders the progress of an associative nucleophilic (S N 2) displacement. The factors discussed in the above paragraph, however, do not prevent a sterically-hindered carbon from being a good electrophile - they only make ...Nucleophiles. This is the second type of reagent or the carbon compound. This type of substrate molecule has an electron-rich region and thus they attack the electron deficient region of another substrate molecule. Nucleophiles have an electron-rich region and are often negatively charged. Nevertheless, some neutral molecules containing an atom ... Some common conjugate acid–base pairs are shown in Figure 2.3.4 2.3. 4. Figure 2.3.4 2.3. 4: The strongest acids are at the bottom left, and the strongest bases are at the top right. The conjugate base of a strong acid is a very weak base, and, conversely, the conjugate acid of a strong base is a very weak acid. 8.7.1 Electrophiles. Electrophiles are molecules that are deficient in electrons pair with a positive charge, which allows them to react by sharing electron pairs with electron-rich atoms in nucleophiles. Important electrophiles are epoxides, hydroxyamines, nitroso and azoxy derivatives, nitrenium ions, and elemental sulfur.Aug 21, 2023 ... Electrophilic addition reactions often involve unsaturated compounds like alkenes and alkynes, while nucleophilic addition reactions typically ...In order for the nucleophile to attack the electrophile, it must break free, at least in part, from its solvent cage. The lone pair electrons on the larger, less basic iodide ion interact less tightly with the protons on the protic solvent molecules - thus the iodide nucleophile is better able to break free from its solvent cage compared the ...Examples of soft electrophiles are C-X, Br₂, and I₂. Electrophile/nucleophile reactions are better when matched in hardness. The C-X bond is soft so a soft ...Kendall's tau-b provides a measure of the effect size of the relationship between electrophile and nucleophile explanation sophistication: τ b = 0.402 (strong), p < 0.001. This finding suggests that while the levels of explanation of sophistication are related between electrophiles and nucleophiles, the relationship is not perfect (i.e., τ b ...From Wikipedia, the free encyclopedia. In chemistry, an electrophile is a chemical species that forms bonds with nucleophiles by accepting an electron pair. [1] Because electrophiles accept electrons, they are Lewis acids. [2] Most electrophiles are positively charged, have an atom that carries a partial positive charge, or have an atom that ... In this video, Dr. Norris goes over some practice problems in identifying electrophiles and nucleophiles.Their orbitals do not necessarily overlap very well with the electrophile's accepting orbital, but the electrostatic attraction directs them and aids the reaction. Similarly, examples of hard electrophiles are H⁺, Li⁺, Na⁺, and Mg²⁺. Soft nucleophiles usually have large, polarizable orbitals with low charge densities.For example, HBr would be an electrophile as the Bromine in this compound pulls on the shared electrons, causing a positive charge around H and a negative ...Nucleophile vs. Electrophile. A nucleophile is a species that is rich in electrons and can donate them to an electrophile. Like an electrophile, a nucleophile can undergo addition and substitution reactions. One can tell if a reaction is electrophilic or nucleophilic by looking at the regents in a chemical reaction. A nucleophile has a full or partial negative charge, while an electrophile has a full or partial positive charge. What does nucleophilic and electrophilic mean?Explanation: Because of the difference in electronegativity, we could represent the hydrogen bromide molecule as +δH − Brδ−; the hydrogen is conceived to have a partial positive charge and tends to react with electron-rich species such as olefins, or hydroxide ions. With olefins: RCH = CH 2 +H −Br → Br− + RH +C −CH 3.In order for the nucleophile to attack the electrophile, it must break free, at least in part, from its solvent cage. The lone pair electrons on the larger, less basic iodide ion interact less tightly with the protons on the protic solvent molecules - thus the iodide nucleophile is better able to break free from its solvent cage compared the ...Jul 4, 2011 ... jp313 said: How do you quickly recognize a nucleophile and electrophile molecule without seeing the positive and negative charge?A vacant p orbital (e.g. boron) also makes a molecule electrophilic. Regardless, the nucleophile needs an electrophile's empty orbital to interact with. In any ...A base is a body that proceeds with an acid in an acid-base reaction. Whereas, the nucleophile is a chemical class of an atom or molecule that shape tied with electrophiles by contributing an electron set. Although base and nucleophile both are electron-rich species and are pretty similar, they are not the same.Take home points on electrophiles: 1) They want electrons, meaning they are electron deficient, in order to form a new bond. 2) They are attacked by nucleophiles. 3) They are positively charged (or have a partial positive), polar and/or polarizable. 4) They become even better electrophiles in the presence of Lewis acids.Electrophiles react by accepting an electron pair in order to form a bond to a nucleophile including the interactions of a proton and a base. Electrophiles are ...Video transcript. - [Instructor] In the last video, we learned about nucleophiles and electrophiles. And in this video, we're gonna look at some simple organic chemistry mechanisms and learn to identify the electrophiles and nucleophiles and also think about how to show the movement of electrons during a mechanism. من المصطلحات المهمة، في الكيمياء العضوية النظري Organic chemistry، وتحديداً في ميكانيكات التفاعلات العضوية، هما ... History Nucleophile vs Electrophile Explained Applications Examples for Nucleophile vs Electrophile FAQs History A British chemist named Christopher Kelk Ingold from …Electrophiles. In the vast majority of the nucleophilic substitution reactions you will see in this and other organic chemistry texts, the electrophilic atom is a carbon which is bonded to an electronegative atom, usually oxygen, nitrogen, sulfur, or a halogen. The concept of electrophilicity is relatively simple: an electron-poor atom is an ...LES REACTIONS D'ADDITION : 🧪 Nucléophile, électrophile et radicalaire ! Coaching by Anty ️ https://coaching-by-anty.com/ Rejoins le groupe d'entraide su...12.4: Reactions Between Nucleophiles and ElectrophilesOrganic reactions are kind of like carefully choreographed fight scenes, and nucleophilic attack is a key move. This episode of Crash Course Organic Chemistr... Jan 11, 2015. Yes, alkenes are nucleophiles. The π bond is localized above and below the C-C σ bond. These π elecrons are relatively far from the nuclei and are loosely bound. An electrophile can attract those electrons and pull them away to form a new bond. The double bond acts as a nucleophile (Lewis base) when it attacks the electrophile.Jul 20, 2022 · What is a nucleophile? A nucleophile is an atom or functional group with a pair of electrons (usually a non-bonding, or lone pair) that can be shared. The same, however, can be said about a base: in fact, bases can act as nucleophiles, and nucleophiles can act as bases. What, then, is the difference between a base and a nucleophile? A Brønsted ... Jul 5, 2017 · The part that the nucleophile is going to be attached is called an electrophile. This electrophile lacks electrons in order to become stable. Therefore, it accepts electrons from a nucleophile. This results in the formation of a covalent bond between nucleophile and electrophile. Most of the times, the nucleophile is negatively charged. Jan 26, 2024 · Identify nucleophiles and electrophiles, their similarities, and differences from acids and bases. Understand S N 2, E2, S N 1, or E1 reaction mechanisms, factors that affect them, and conditions that dictate which one will take place. Learn some examples of S N 2, E2, S N 1, and E1 reactions of alcohols, ethers, amines, and thiols. For example, HBr would be an electrophile as the Bromine in this compound pulls on the shared electrons, causing a positive charge around H and a negative ...The part that the nucleophile is going to be attached is called an electrophile. This electrophile lacks electrons in order to become stable. Therefore, it accepts electrons from a nucleophile. This results in the formation of a covalent bond between nucleophile and electrophile. Most of the times, the nucleophile is negatively charged.Learn the definitions, examples, and identification of nucleophiles and electrophiles, the two types of reactive species in organic chemistry. Nucleophiles are electron donors and …Jan 23, 2023 · Protonation states and nucleophilicity. The protonation state of a nucleophilic atom has a very large effect on its nucleophilicity. This is an idea that makes intuitive sense: a hydroxide ion is much more nucleophilic (and basic) than a water molecule, because the negatively charged oxygen on the hydroxide ion carries greater electron density than the oxygen atom of a neutral water molecule. Additional slide nucleophile, electrophile, free radical. 1. A VERY BRIEF INTRODUCTION. 2. MEET THE ATTACKERS Press the space bar. 3. MEET THE ATTACKERS I AM A NUCLEOPHILE I HAVE A LONE PAIR WHICH I CAN USE TO FORM A NEW BOND. I ATTACK ELECTRON DEFICIENT AREAS (those with a + or d+)Their orbitals do not necessarily overlap very well with the electrophile's accepting orbital, but the electrostatic attraction directs them and aids the reaction. Similarly, examples of hard electrophiles are H⁺, Li⁺, Na⁺, and Mg²⁺. Soft nucleophiles usually have large, polarizable orbitals with low charge densities. Table of Contents A Nucleophile Is A Reactant That Provides A Pair Of Electrons To Form A New Covalent Bond An Electrophile Is A Reactant That Accepts A …NH2 is a nucleophile.Nucleophiles are species that have a lone pair of electrons and are capable of donating these electrons to form a new bond. They are attracted to positively charged atoms or molecules, known as electrophiles. On the other hand, electrophiles are species that can accept a pair of electrons and are attracted to nucleophiles.1.Classification des espèces selon leur caractères nucléophile fort/faible et base forte/faible.Retrouvez des milliers d'autres cours et exercices interactifs ...the alkene is a nucleophile and bromine is acting as an electrophile and the mechanism step is an example of “Make a bond between a nucleophile and electrophile”. Note that a lone pair on bromine simultaneously makes a second new bond with the alkene to give the three-membered ring reaction intermediate. Also notice that the Br Learn for free about math, art, computer programming, economics, physics, chemistry, biology, medicine, finance, history, and more. Khan Academy is a nonprofit with the mission of providing a free, world-class education for anyone, anywhere. Terms in this set (5) electrophile. any molecule, ion or atom that is electron deficient in some way (electron-loving) ex: H+, Zn2+, Fe3+, BH3, BF3, Br2, Cl2, etc. nucleophile. molecule or ion that donates a pair of electrons to form a new covalent bond. ex: NaOH, NaNH2, NaCN, NaN3, X-, alcohols, etc.𝐃𝐨𝐰𝐧𝐥𝐨𝐚𝐝 𝐀𝐓𝐏 𝐒𝐓𝐀𝗥 𝐀𝐩𝐩 𝐟𝐨𝐫 Unlimited free practice for IIT 𝐉𝐄𝐄 📱 𝐀𝐓𝐏 𝐒𝐓𝐀𝗥 𝗔𝗽𝗽 ...A nucleophile is a chemical species that can donate a pair of electrons to a different chemical species (generally to an electrophile) to form a chemical ...See full list on khanacademy.org This is the type encountered in ch. 6 in Sn2 reactions. Examples are many primary and secondary halides. The outcome of the reaction between a nucleophile and this type of electrophile is a substitution product. If the nucleophile used is a carbon nucleophile, the product has an expanded carbon chain because a new carbon-carbon bond has been ...من المصطلحات المهمة، في الكيمياء العضوية النظري Organic chemistry، وتحديداً في ميكانيكات التفاعلات العضوية، هما ...Jan 23, 2023 · The O of - OH is a better nucleophile than the O of H 2 O, and results in a faster reaction rate. Similarly, when nitrogen is part of NH 2, it bears a negative charge, and when it is part of NH 3, it is neutral. The N of NH 2 is a better nucleophile than the N of NH 3, and results in a faster reaction rate. May 18, 2020 · A negatively charged species is usually a stronger nucleophile or base than its neutral analog. Thus, hydroxide ion is stronger, both as a base and as a nucleophile, than water. 3. Carbon bonded to a metal has strong negative character, revealed when writing resonance structures. The carbon atom in such molecules is considered a strong nucleophile. Terms in this set (5) electrophile. any molecule, ion or atom that is electron deficient in some way (electron-loving) ex: H+, Zn2+, Fe3+, BH3, BF3, Br2, Cl2, etc. nucleophile. molecule or ion that donates a pair of electrons to form a new covalent bond. ex: NaOH, NaNH2, NaCN, NaN3, X-, alcohols, etc.When a nucleophile reacts with an electrophile, the movement of electrons can be shown with a curved arrow. Identifying nucleophiles is an important skill to master when studying organic chemistry.6.5. Lewis acids & bases, electrophiles & nucleophiles. Acids and bases are an important part of organic chemistry. One of the most applicable theories is the Lewis acid/base motif that extends beyond the Br ø nsted-Lowry definition described in the previous section. Oct 9, 2020 · ELECTROPHILE VS NUCLEOPHILE : 🧪 Comment les différencier en REACTIVITE CHIMIQUE ? Coaching by Anty ️ https://coaching-by-anty.com/ Rejoins le groupe d'e... Electrophiles are neutral species deficient in electrons. They can accept a couple of electrons. An electrophile is also perceived as a species that loves electrons (philic). The term can be split into “electro” (derived from electron) and “phile” (which means loving). Electrophiles are either positively charged or neutrally charged.Oct 9, 2020 · ELECTROPHILE VS NUCLEOPHILE : 🧪 Comment les différencier en REACTIVITE CHIMIQUE ? Coaching by Anty ️ https://coaching-by-anty.com/ Rejoins le groupe d'e... Some common conjugate acid–base pairs are shown in Figure 2.3.4 2.3. 4. Figure 2.3.4 2.3. 4: The strongest acids are at the bottom left, and the strongest bases are at the top right. …
Explain the different between a nucleophile and electrophile and give an example of each. A nucleophile is electron rich like an alkene or amine and an electrophile is electron poor, i.e. a carbocation with an empty p-orbital. Two possible products can be formed in the following reaction. Label the nucleophile and electrophile in this reaction .... Cryptobase bitcoin a
Jul 3, 2017 ... The main difference between electrophile and nucleophile is that electrophiles are atoms or molecules that can accept electron pairs whereas ...Differences between nucleophile-electrophile and acid-base. The base is a substance that donates a pair of electrons to a proton to make a covalent bond. So, a base is a sub-class of nucleophiles and an acidic proton is a subclass of electrophiles. Acid-base reactions are fast reactions. In acid-base reactions, emphasis is on thermodynamic ...S N 1 / S N 2 / E1 / E2 The Nucleophile / Base. This article assumes you understand the mechanisms of the S N 1/S N 2/E1 and E2 reactions. For review, see here [S N 1] [S N 2] [] []S N 1/S N 2/E1/E2 reactions tend to happen on alkyl halides [see Identifying Where Substitution and Elimination Reactions Happen]; Determining whether the alkyl …Solution. Electrophiles are electron deficient species and can accept an electron pair from electron rich species.Examples include carbocations and carbonyl compounds. A nucleophile is electron rich species and donates electron pairs to electron deficient species. Examples include carbanions, water , ammonia, cyanide ion etc.The part that the nucleophile is going to be attached is called an electrophile. This electrophile lacks electrons in order to become stable. Therefore, it accepts electrons from a nucleophile. This results in the formation of a covalent bond between nucleophile and electrophile. Most of the times, the nucleophile is negatively charged.For example, HBr would be an electrophile as the Bromine in this compound pulls on the shared electrons, causing a positive charge around H and a negative ...A vacant p orbital (e.g. boron) also makes a molecule electrophilic. Regardless, the nucleophile needs an electrophile's empty orbital to interact with. In any ...Jun 5, 2012 · Table of Contents A Nucleophile Is A Reactant That Provides A Pair Of Electrons To Form A New Covalent Bond An Electrophile Is A Reactant That Accepts A Pair Of Electrons To Form A New Covalent Bond Nucleophilicity” And “Electrophilicity” Refer To The Extent To Which A Species Can Donate Or Accept A Pair Of Electrons nucleophile, in chemistry, an atom or molecule that in chemical reaction seeks a positive centre, such as the nucleus of an atom, because the nucleophile contains an electron pair available for bonding. Examples of nucleophiles are the halogen anions (I -, Cl -, Br - ), the hydroxide ion (OH - ), the cyanide ion (CN - ), ammonia (NH 3 ), and ...Nov 30, 2012 · 2. “Strong” vs. “Weak” Nucleophiles / Bases. Now that we have had some practice in identifying the likely nucleophile, I am going to suggest a somewhat rough but very helpful classification that will help in distinguishing S N 1/E1 reactions from S N 2/E2 reactions. Electrophile. Nucleophile. Species with insufficient electrons are known as electrophiles. An electron-rich species are known as a nucleophile. The letter E is used to indicate electrophiles. The letter Nu- is used to indicate nucleophiles. An electrophile undertakes both electrophilic addition and electrophilic substitution processes.Their orbitals do not necessarily overlap very well with the electrophile's accepting orbital, but the electrostatic attraction directs them and aids the reaction. Similarly, examples of hard electrophiles are H⁺, Li⁺, Na⁺, and Mg²⁺. Soft nucleophiles usually have large, polarizable orbitals with low charge densities.Difference between Nucleophile and Base. A nucleophile is nucleus loving specie. It always attacks an electrophile to initiate a reaction whereas, a base is a specie that accepts the proton or it attacks an acidic hydrogen. For more details, please visit: Nucleophile vs BaseMay 18, 2020 · Ammonia is a moderately good nucleophile but also a good base. Given the choice, it prefers to act as a base. acid-base equilibrium favors the left side because bromide ion is a weak base. Bromide ion is an effective nucleophile, preferring to attack the electrophilic carbon displacing the water. Ammonia is a weak nucleophile and a moderate base. The attacking reagent may be a nucleophile or an electrophile. ... The attack of the electrophiles may result in the formation of a bond between the electrophile and the activated unsaturated substrate, in which case it is called electrophilic addition, or may result in an abstraction of a part or the whole of the activated ligand, in which ...2. Nucleophile คืออะไร 3. Electrophile คืออะไร 4. การเปรียบเทียบแบบเคียงข้างกัน - Nucleophile vs Electrophile ในรูปแบบตาราง 5. สรุปTruong-Son N. Nov 21, 2015. Although both do accept electrons, there is indeed a difference. The purpose of an acid is to take electrons in order to donate a proton. The purpose of an electrophile is to take electrons in order to make a significant bond. Another way to say it is that an acid participates in a chemical reaction "passively" (it ...nucleophile, in chemistry, an atom or molecule that in chemical reaction seeks a positive centre, such as the nucleus of an atom, because the nucleophile contains an electron pair available for bonding. Examples of nucleophiles are the halogen anions (I -, Cl -, Br - ), the hydroxide ion (OH - ), the cyanide ion (CN - ), ammonia (NH 3 ), and ....